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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RGS19
All Species:
29.7
Human Site:
Y143
Identified Species:
65.33
UniProt:
P49795
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49795
NP_001034556.1
217
24636
Y143
D
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
Chimpanzee
Pan troglodytes
XP_514823
182
21112
E109
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
S
Rhesus Macaque
Macaca mulatta
XP_001113240
344
37919
Y270
D
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
Dog
Lupus familis
XP_548528
178
20519
E105
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX84
216
24659
Y143
D
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
Rat
Rattus norvegicus
O70521
216
24719
Y143
D
E
K
A
R
L
I
Y
E
D
Y
V
S
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514576
273
31036
Y184
E
E
K
A
K
L
I
Y
D
N
Y
I
S
S
L
Chicken
Gallus gallus
Q9PWA1
218
25123
Y145
E
E
K
A
R
L
I
Y
E
D
Y
I
S
I
L
Frog
Xenopus laevis
A1A643
201
23280
Y128
R
C
K
A
N
V
I
Y
Q
E
F
I
Q
P
N
Zebra Danio
Brachydanio rerio
Q6DGI0
174
20503
E101
K
A
N
K
I
Y
K
E
F
I
D
V
H
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49808
169
19576
Y96
E
E
K
A
R
I
I
Y
E
D
F
I
S
I
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.8
61.9
74.6
N.A.
91.2
90.3
N.A.
47.9
59.1
30.8
29.4
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
100
81.1
62.5
79.2
N.A.
93.5
93
N.A.
61.1
70.6
51.6
50.2
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
60
86.6
26.6
6.6
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
33.3
100
33.3
N.A.
100
100
N.A.
93.3
100
60
6.6
N.A.
N.A.
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
73
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
0
0
0
0
0
0
0
28
55
10
0
0
0
0
% D
% Glu:
46
64
0
0
0
0
0
28
55
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
19
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
28
73
0
0
10
0
37
19
55
0
% I
% Lys:
10
19
73
10
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
19
55
0
0
0
0
0
0
0
19
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Q
% Arg:
10
0
0
19
55
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
19
64
10
19
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
19
46
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
19
73
0
19
55
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _